How does American Telehealth Review score telehealth providers?

Every provider is scored on a uniform v3.0 six-pillar rubric: Clinical Quality (25 points), Pricing & Value (20 points), Patient Experience (15 points), Safety & Compliance (15 points), Transparency (15 points), and Continuity of Care (10 points). Total possible score is 100 points.

How often are scores updated?

Every provider is fully re-scored every 90 days. Material events such as pricing changes or FDA actions trigger an off-cycle re-scoring within 14 days.

Can providers pay to improve their score?

No. The v3.0 rubric is applied uniformly across all providers. Pillar weights cannot be modified, and Editor's Pick selection is based exclusively on score plus qualitative review.

Journal · Evidence review

Muscle Loss on GLP-1s: What the Research Shows and How to Protect Lean Mass

What current research shows about lean-mass loss during GLP-1 weight loss, and evidence-informed ways to protect muscle.

Published by Ranika Editorial Group LLCUpdated June 1, 2026

Direct Answer

Do GLP-1 medications cause muscle loss?

Some of the weight lost on GLP-1 medications is lean mass, as with most substantial weight loss. Research suggests a meaningful share of total weight lost can come from fat-free mass, which is why protein intake and resistance exercise are commonly recommended alongside treatment. Discuss a plan with your clinician.

Disclaimer: American Telehealth Review is an editorial resource and does not provide medical advice, diagnosis, or treatment. Compounded medications are not FDA-approved finished drug products and should only be prescribed when clinically appropriate by a licensed healthcare provider. Brand-name medications such as Ozempic, Wegovy, Mounjaro, and Zepbound are FDA-approved under their own applications. Compounded semaglutide and compounded tirzepatide are not FDA-approved finished drug products.

What the evidence indicates

Rapid weight loss of any kind reduces both fat and lean mass. Trials and analyses of GLP-1 therapy show lean-mass changes, and research into muscle-preserving strategies and adjunct agents is ongoing. The clinical priority is preserving function and strength.

Evidence-informed protection

Adequate protein intake, resistance training, and gradual, supervised titration are widely recommended to protect lean mass during GLP-1 weight loss. A provider that includes coaching and follow-up supports this.

Frequently asked questions

Is muscle loss on GLP-1s avoidable?

Some lean-mass loss accompanies major weight loss, but protein intake and resistance exercise help preserve muscle. Discuss with your clinician.

Should I lift weights on a GLP-1?

Resistance training is commonly recommended to help protect lean mass during weight loss; follow personalized medical advice.

Sources

Wilding JPH et al. Once-weekly semaglutide in adults with overweight or obesity (STEP 1). N Engl J Med. 2021.
Jastreboff AM et al. Tirzepatide once weekly for the treatment of obesity (SURMOUNT-1). N Engl J Med. 2022.
U.S. FDA — Medications containing semaglutide and tirzepatide; Compounding and the FDA (fda.gov).