Ozempic vs Mounjaro

Comparison: Ozempic vs Mounjaro

Both are reviewed at American Telehealth Review against published clinical evidence and FDA labeling.

Key differentiators

• Active ingredient: Ozempic = semaglutide; Mounjaro = tirzepatide.
• Mechanism: Ozempic GLP-1; Mounjaro dual GLP-1/GIP.
• HbA1c reduction: SURPASS-2 head-to-head: tirzepatide superior.
• Weight loss: tirzepatide ~47% greater than semaglutide 1 mg in SURPASS-2.

Other comparisons

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