Key facts
Mechanism of action
GHRH analog comprising the first 29 amino acids of human growth hormone-releasing hormone. Stimulates endogenous GH release. Was FDA-approved (Geref) but discontinued; now dispensed via compounding pharmacies.
Standard dosing
Typical clinical use: 200-500 mcg SC nightly. Dosing varies by indication and provider protocol; this is reference-only and not a prescribing recommendation. Sermorelin requires a prescription from a licensed clinician.
Regulatory status & pharmacy pathway
Not currently FDA-marketed (was approved as Geref). FDA limits which peptides a pharmacy may compound; check this page’s dated FDA status notice before assuming a peptide is legally available. Ask which licensed pharmacy fills the prescription and check that pharmacy’s license with your state board of pharmacy.
U.S. telehealth providers prescribing Sermorelin
The most commonly cited U.S. telehealth providers for Sermorelin are Defy Medical, Marek Health, Hone Health, Maximus, and PeterMD —, whose offerings for this peptide we have not verified (see the FDA status notice above). See the full provider directory for complete profiles.
Trade-offs to know
Sermorelin carries the trade-offs common to all compounded peptide therapeutics: not FDA-approved, cash-pay only, no in-network insurance coverage, and pharmacy-quality variation between providers. Choose a prescriber that names its pharmacy, explains its follow-up schedule and states the regulatory status of what it prescribes.
Related peptides in the growth hormone category
Editorial team
Researched by Dr. Parmis (Medical Researcher, Western University of Health Sciences); medically reviewed by Dr. Jonathan Snipes, MD and Kim Callender, NP (FNP-BC).