Where can I find the primary clinical evidence?

Primary trials are published in peer-reviewed journals (NEJM, JAMA, Lancet) with PubMed PMIDs cited throughout American Telehealth Review.

Side Effects — Detailed Profile | American Telehealth Review

Side Effects

Most common: nausea (44%), diarrhea (30%), vomiting (24%), constipation (24%). Mostly mild-moderate and titration-dependent. Serious AEs <1% in published cohorts.

Clinical referencePubMed-linkedUpdated 2026-06-01

Editorial team

Dr. Sam Saberian · Lead Medical Researcher

Medical review by Alen A. Schwartz, MD · Edited by Julliana Edwards · Last updated 2026-06-01

Overview

Most common: nausea (44%), diarrhea (30%), vomiting (24%), constipation (24%). Mostly mild-moderate and titration-dependent. Serious AEs <1% in published cohorts.

PubMed citations

PMID 33567185

Related clinical pages

STEP trial results
SELECT trial results
FLOW trial results
Mechanism of action
Dosing & pharmacology
Contraindications
Side effects